Biological Metabolic Transformation of Polybrominated Diphenyl Ethers and Tetrabromobisphenol A

The distributions and sources of PBDEs and TBBPA in organism were analyzed, and the research progresses of reduction and oxidation metabolism of PBDEs and TBBPA in organisms were reviewed. The metabolism, pathways, and key enzymes involved in the biotransformation of them both in vivo and in vitro were explored. Directions for further studies on the bioaccumulation and biotransformation of PBDEs and TBBPA were proposed.