Abstract: This study selected four fully operational domestic coal-to-ethylene glycol (CTEG) enterprises as research objects. The investigated enterprises adopt two indigenous and one foreign production processes, covering three types of syngas preparation technologies and two raw gas production routes. Based on a comparative analysis of the three domestic and overseas syngas preparation technologies via the life cycle assessment (LCA) method, this study further conducted a comparative investigation between syngas and coke oven gas raw materials, and systematically analyzed the heterogeneity of energy, carbon, and water footprints of ethylene glycol products under diverse technology-raw material coupling schemes. The results indicate that among the three selected syngas-based preparation technologies,domestic technologies offered the best overall environmental benefits, with energy, carbon, and waterfootprints being 25.8%, 24.1%, and 9.4% lower than those of foreign technologies, respectively. The coalconversion stage contributed 87%-94%, 63%-81%, and 41%-70% to the energy, carbon, and water footprints,respectively. By using coke oven gas as a feedstock, energy, carbon, and water footprints were reduced by 15.5%, 73.4%, and 56.1%, respectively, although it substantially increased the contribution of the feedstock supply stage to the carbon and water footprints. Existing enterprises can significantly reduce carbon emissions by improving theefficiency of ethylene glycol synthesis through methods such as co-supplying syngas with coke oven gas, shale gas, and other hydrogen-rich resources. These findings can provide scientific data and a decision-making basis for therational layout, technology selection and green upgrading of China's CtEG industry.